He Yungang

Young Investigator; Computational Biology and Population Genetics of Genome and Individual Phenotypic Diversity

Contact Information:

Address: Room #407, MinDao Building, Fudan University

130 DongAn Road, Shanghai, 200031 China

Fax: 86-21-54237296,

Email: heyungang@fudan.edu.cn

Education Background

Sep., 2002 – Jun., 2005 School of life sciences, Fudan University

Ph.D. in Population Genetics

Sep., 1999 – Jul., 2002 School of life sciences, Yunnan University

M.S. in Zoology

Sep., 1995 – Jul., 1999 Biology Department, Yunnan University

B.S. in Biology

Professional Experience:

Apr., 2006 – Apr., 2008 Stanford Research Institute International (SRI International)

San Francisco, U.S.A.

Postdoctoral Fellow

Aug., 2008 – Nov., 2009 CAS-MPG partner institute for computational biology

Shanghai, China

Assistant Professor

Dec., 2009 – Dec., 2017 CAS-MPG partner institute for computational biology

Shanghai, China

Associate Professor

Jan., 2018 – Mar. 2023, Institutes of Biomedical Sciences, Fudan University

Shanghai, China

Tenure-track Associate Professor

Apr., 2023 – Dec., 2023, Intelligent Medicine Institute, Fudan University

Shanghai, China

Tenure-track Associate Professor

Jan., 2024 – Present, Intelligent Medicine Institute, Fudan University

Shanghai, China

Tenured Professor

Grants & Awards:

Grants

2006 Postdoctoral Fund of Stanford Research Institute

2009 Science and Technology Committee of Shanghai Municipality (09ZR1437000)

2010 Shanghai Institutes of Biological Sciences (2010KIP206)

2011 National Science Foundation of China (81100997, 31171279); 

Fund for Member of Youth Innovation Promotion Association, Chinese Academy of Science

2014 National Science Foundation of China (91331109)

2016 Fund for Outstanding Member of Youth Innovation Promotion Association, Chinese Academy of Science

2018 National Science Foundation of China (91731310)

2019 National Science Foundation of China (31871255)

2022 National Science Foundation of China (32170634)

2024 National Science Foundation of China (32370670)

Awards

2010 Young Faculty Award, Sanofi- Shanghai Institutes for Biological Sciences

2012 The First Prize of Natural Science Award (4th), Chinese Ministry of Education

2012 Member of Youth Innovation Promotion Association, Chinese Academy of Science

2015 The Second Prize of National Natural Science Award (4th), the State Council of the People’s Republic of China

2016 Outstanding Member of Youth Innovation Promotion Association, Chinese Academy of Science

Selected Publications (since 2019):

1. Duan A, Li J, Yang Z, He Y, 2023. The defense of Shangri-La: Protecting isolated communities by periodic infection screening in the worst future pandemic. Infection, Genetics and Evolution 113, 105479 (corresponding author)

2. Chen H, Lin R, Lu Y, Zhang R, Gao Y, He Y, Xu S, 2022. Tracing Bai-Yue ancestry in aboriginal Li people on Hainan Island. Mol Biol Evol msac210. https://doi.org/10.1093/molbev/msac210. (co-corresponding author)

3. Xu F, Wang Y, Ling Y, Zhou C, Wang H, Teschendorff AE, Zhao Y, Zhao H, He Y, Zhang G, 2022. dbDEMC 3.0: Functional exploration of differentially expressed miRNAs in cancers of human and model organisms. Genomics, Proteomics & Bioinformatics. 2022 Jun;20(3):446-454 (co-corresponding author)

4. Yang Z, Xu F, Teschendorff AE, Zhao Y, Yao L, Li J, He Y, 2022. Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation. Front Mol Biosci 9, 1067406.

5. Yang Z, Xu F, Xue A, Lv H, He Y, 2022. Degree of Freedom of Gene Expression in Saccharomyces cerevisiae. Microbiology Spectrum 10, e00838-21. (corresponding author)

6. Yang Z, Xu F, Li H, He Y. Beyond Samples: A Metric Revealing More Connections of Gut Microbiota Between Individuals. Comput Struct Biotec. 2021 Jul 10;19:3930-3937. doi: 10.1016/j.csbj.2021.07.009. (corresponding author)

7. Dong H, Zhu Y, Shen Y, Xie S, He Y, Lu L. High prevalence of tryptophan-truncated S quasispecies in treatment-naïve chronic hepatitis B patients. J Gen Virol. 2021 Jul;102(7). doi: 10.1099/jgv.0.001623. (co-corresponding author)

8. Yang Z, Xu F, Wang H, Teschendorff AE, Xie F, He Y. Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation. EBioMedicine. 2021 Jun;68:103399. doi: 10.1016/j.ebiom.2021. 103399. (co-corresponding author)

9. Shi T, Zhou J, Xue A, Lu H, He Y, Y Y, Characterization and modulation of endoplasmic reticulum stress response target genes in Kluyveromyces marxianus to improve secretory expressions of heterologous proteins. Biotechnol Biofuels, 14(1) (2021):236.

10. Huang X, Wang S, Jin L, He Y. 2021. Dissecting dynamics and differences of selective pressures in the evolution of human pigmentation. Biol Open. Feb 9;10(2):bio056523. (co-corresponding author)

11. Zhang C, Li Q, Xu T, Li W, He Y, Gu H, 2021. New DNA-hydrolyzing DNAs isolated from an ssDNA library carrying a terminal hybridization stem. Nucleic Acids Res., 49(11):6364-6374

12. Li H, Wang S, Zhong F, Bao W, Li Y, Liu L, Wang H, He Y. Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China. Front Med (Lausanne). 2020 Apr 30;7:190. doi: 10.3389/fmed.2020.00190. (corresponding author)

13. Mo W, Wang M, Zhan R, Yu Y, He Y, Lv H. Kluyveromyces marxianus developing ethanol tolerance during adaptive evolution with significant improvements of multiple pathways. Biotechnol Biofuels. 2019 Mar 22;12:63. doi: 10.1186/s13068-019-1393-z. eCollection 2019. (co-corresponding author)

14. Huang X, Jin L, He Y, 2019. SeleDiff: A fast and scalable tool for estimating and testing selection differences between populations. Journal of Open Source Software, 4(39), 1545